Rapid and green synthesis of 4H-benzo[b]pyrans using ...
4H-benzo[b]pyrans were obtained rapidly in high yields using triethanolamine as an efficient, eco-friendly and low-cost basic catalyst. One-pot three-component condensation reaction of a series of aldehydes, malononitrile and 1,3-diketones was performed at room temperature. All the products were obtained in high-to-excellent yields and characterized in detail.
Cysteic acid grafted to magnetic graphene oxide as a ...
Recent catalytic systems for the synthesis of 4H-chromene derivatives consist of Fe(HSO 4) 3 28, nickel nanoparticles 29, ZrO 2 nanoparticles 30, Zn 4 O(H 2 N-TA) 3 31, ZnS nanoparticles 32, nano ...
Synthesis, biological assessment and molecular modeling of ...
The synthesis and pharmacological evaluation of racemic 14-aryl-10,11,12,14-tetrahydro-9H-benzo[5,6]chromeno[2,3-b]quinolin-13-amines (19-28), prepared by Friedländer reaction of 3-amino-1-aryl-1H-benzo[f]chromene-2-carbonitriles (10-18) with suitable cycloalkanones is described. These molecules are …
American Scientific Publishers - Journal of Computational ...
X-ray, Microwave Assisted Synthesis and Spectral Data of 3-Amino-1-(3,5-dibromo-2-methoxy phenyl)-8-methoxy-1H-benzo[f]chromene-2-carbonitrile Abd El-Galil E. Amr, Heba K. Abd El-Mawgoud, Ahmed M. El-Agrody, Mohamed A. Al-Omar, and Mohamed S. Alsultan J. Comput. Theor. Nanosci. 14, 3930–3935 (2017)
4-Aryl-4H-naphthopyrans derivatives: one-pot synthesis ...
Background: A series of 2-amino-4-aryl-4H-benzo[h or f]chromene-3-carbonitrile derivatives were synthesized and evaluated for inhibition of Src kinase and cell proliferation in breast carcinoma (BT-20) cell lines. Methods: The one-pot, three-component reaction of α or β-naphthol, malonitrile and an aromatic aldehyde in the presence of diammonium hydrogen phosphate …
Structures of some synthetically... | Download Scientific ...
The widespread biological properties of dihydropyrano[3,2-c]chromenes, 2-amino-4-aryl-4H-benzo[h]chromenes, and 3-amino-1-aryl-1H-benzo[f]chromenes have …
Synthesis, reactions and antimicrobial activities of 8 ...
Synthesis of 2-(2-(4-methoxyphenyl)hydrazono)-2-(4-(8-ethoxycoumarin-3-yl)thiazol-2-yl)acetonitrile hydrobromide (28). Method A: To a solution of compound 20c (10 mmol) in methanol (20 mL), a combination of 4-methoxyaniline (10 mmol), hydrochloric acid (5 mL) and sodium nitrite (10 mmol) in glacial acetic acid (20 mL) at 0 °C was added ...
The One-Step Synthesis of 3,4-Dihydropyrano[F]Chromene ...
Table 1: 3-amino-1-phenyl-1H-benzo[f]chromene-2-carbonitrile 4a–g in under grinding using DABCO Yields refer to pure isolated products characterized b y IR, 1 H and 13 C N MR spectroscopy and mass spectrometry. The structures of compounds 4 were deduced from their 1 H NMR, 13 C NMR and IR spectral data and their molecular weight confirmed by mass …
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(PDF) Grindstone Chemistry: An Efficient and Green ...
A single step, mild, environmentally friendly green method has been developed for the synthesis of. physiologically active 2-amino-4 H-benzo [b]pyrans employing solid sodium ethoxide as …
2-Aminobenzothiazole | C7H6N2S - PubChem
If released to the atmosphere, 2-aminobenzothiazole is expected to exist solely as a vapor, based on an estimated vapor pressure of 1.1X10-4 mm Hg. Vapor-phase 2-aminobenzothiazole is expected to degrade quickly by reaction with photochemically produced hydroxyl radicals (estimated half-life of 0.64 hours).
Organocatalysis in synthesis: L-proline as an ...
2. Results and Discussion. First in an attempt to synthesize the chiral pyranopyrazoles 4, we have reacted benzaldehyde (1), malononitrile (2) and pyrazolon-5-one (3) with 10% mol L-proline as the only catalyst. In contrast to Muramulla et al's. findings that for the same reaction using L-proline alone as a catalyst under the reported reaction conditions no …
Heat sensitive recording composition containing a ...
2-amino-1-butanol 155-62" aminoethylenethanolamine 74-85 ... (benzo (f) chromene) 2/1 1.9 blue (g) 6'-chloro-8'-methoxybenzoindolino spiropyran 2/1 2.4 blue (h) ... Color developed very early during ball-milling and the mix was a deep blue-grey after 8 hours grinding. This grind was useless in the preparation of a thermo-sensitive coated paper.
Visible light mediated synthesis of 6H-benzo[c]chromenes ...
A synthetic approach towards the 6H-benzo[c]chromene ring under visible light and transition-metal-free conditions has been developed.Benzochromenes are synthesized from the corresponding (2-halobenzyl) phenyl ethers or (2-halophenyl) benzyl ethers using KO t Bu in dimethyl sulfoxide (DMSO) at room temperature (rt) and blue light-emitting diodes (LEDs) as …
An efficient, multicomponent approach for solvent-free ...
Method: The reaction of 3-amino-1-(substitutedphenyl)-1H-benzo[f]chromene-2-carbonitrile with sodium azide, ammonium chloride in dimethyl formamide solvent under reflux condition for …
The Catalytic Activity of TiO 2 Toward a Multicomponent ...
Abstract: Aims: Test the hypothesis that the catalytic activity of TiO 2 nanoparticles towards a liquidphase or mechanoactivated multicomponent reaction can be tuned by visible light and the shape of nanoparticles.. Background: Catalytic multicomponent reactions have been proven to be excellent synthetic approaches to a series of biologically relevant compounds including 2 …
Chromenes: potential new chemotherapeutic agents for ...
Design, synthesis, and anti-breast cancer activity in vivo of 4-amino-2H-benzo[h]chromen-2-one and 4 amino-7,8,9,10-tetrahydro-2H-benzo[h]chromen-2-one analogues with improved water solubility. J. Nat. Prod. 75,370–377 (2012).Crossref, Medline, CAS, Google Scholar; 72 Wang X, Bastow KF, Sun CM et al. Antitumor Agents. 239. Isolation ...
One‐Pot Synthesis of 3‐[(N‐Alkylanilino)(aryl)methyl ...
A simple and highly efficient protocol for the one-pot synthesis of a series of 3-[(N-alkylanilino)(aryl)methyl]indoles has been developed based on low-cost and environmentally benign zirconium oxychloride octahydrate and copper chloride dihydrate catalysts via three-component condensation between indoles, aromatic aldehydes, and N-alkylanilines at room …
Classifications, properties, recent synthesis and ...
Badrey et al., have been reported that the synthesize of azo dyes based on 2-amino-7-hydroxy-4-phenyl-4H-chromene-3-carbonitrile [124,125] has been reached by two routes. 2-amino-7-hydroxy-4-phenyl-4H-chromene-3-carbonitrile was coupled to various diazonium salts which make it possible to obtain the corresponding dyes and then react with ...
Poly(4-vinylpyridine) efficiently catalyzed one-pot four ...
Abstract: An efficient one-pot synthesis of pyrano[2,3-c]pyrazoles via four-component reaction of phenyl hydrazine, ethyl acetoacetate, malononitrile and aromatic aldehydes, catalyzed by poly(4-vinylpyridine) is reported.This method provides many advantages such as, atom-economy, easy work up, clean procedure, short reaction times and high yields of products.
A facile and green three-component synthesis of 2-amino …
A simple, efficient and one-pot method has been developed for the synthesis of densely functionalized aryl derivatives of 2-amino-3-cyano-7-hydroxy-4H- chromene by the domino...
Synthesis, antifungal activity and docking study of 2 ...
A particularly interesting group of chromenes are 2-amino-4 H -benzo [ f ]chromenes which are generally prepared by reaction of malononitrile, aldehydes and naphthols in one-pot procedure.
Pentafluoropropionic Acid: An Efficient and Metal-Free ...
Pentafluoropropionic acid (PFPA) efficiently catalyzes the one-pot, three-component reaction of aromatic aldehyde, malononitrile, and dimedone to yield tetrahydrobenzo[b]pyran derivatives in high yields. This method is of great value because of its easy processing, short reaction time, environmentally, and high yields.
Visible Light Mediated Synthesis of 6H-Benzo[c]chromenes ...
A synthetic approach towards 6H-benzo[c]chromene ring under visible light and transition-metal-free conditions has been developed. Benzochromenes are synthesized from the corresponding (2-halobenzyl) phenyl ethers or (2-halophenyl) benzyl ethers using KOtBu in dimethyl sulfoxide (DMSO) at room temperature (r Synthetic methodology in OBC …
ChemInform: Vol 46, No 24 - Wiley Online Library
ChemInform Abstract: Regioselective Formation of 5-Methylene-6-methoxy-1,4,5,6-tetrahydropyridazines from the [4 + 2]-Cycloaddition Reaction of in situ Generated 1,2-Diaza-1,3-dienes with Methoxyallene. Orazio A. Attanasi, Gianfranco Favi, Fabio Mantellini, Serena Mantenuto, Giada Moscatelli, Simona Nicolini.
CN104419326A - Slurry composition for chemical and ...
The invention discloses a slurry composition including 0.1wt%-10wt% of abradant, 0.01 wt%-1wt% of isothiazole dispersion stabilizer, 0.01wt%-1wt% of benzene carboxylic acid corrosion inhibitor, 0.01wt%-15wt% of amino acid chelate agent, and 0.01wt%-1wt% of complexing agent including acrylamide and aminomethyl propanol.Compared with slurry special for polishing, the …
Silica-Grafted Ionic Liquids as Recyclable Catalysts for ...
Silica-grafted N-propyl-imidazolium hydrogen sulfate ([Sipim]HSO4) is employed as a recyclable heterogeneous ionic liquid catalyst for the synthesis of 3,4-dihydropyrano[c]-chromenes by the reaction of aromatic aldehydes, malononitrile and 4-hydroxycoumarin at 100°C under solvent-free conditions. Also, heterogeneous ionic liquid catalyst was used for the synthesis of pyrano[2,3 …
US4654362A - Derivatives of 2,2'-iminobisethanol - Google ...
amino Prior art date 1983-12-05 Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.) Expired - Lifetime Application number US06/660,355 Inventor Guy R. E. Van Lommen Marcel F. L. De Bruyn Marc F. J. Schroven
L-proline catalyzed green synthesis and anticancer ...
L-proline catalyzed green synthesis and anticancer evaluation of novel bioactive benzil bis-hydrazones under grinding technique Abdelwahed R. Sayeda,b, Sobhi M. Gomha c,d, Hany M. Abd El-lateefa,e and Tariq Z. Abolibdad aDepartment of Chemistry, College of Science, King Faisal University, Al-Ahsa, Saudi Arabia; bChemistry Department, Faculty of Science, ...
A facile and green three-component synthesis of 2-amino-3 ...
A simple, e cient and one-pot method has been developed for the synthesis of densely functionalized aryl derivatives of 2-amino-3-cyano-7-hydroxy-4H-chromene by the domino Knoevenagel-Michael-cyclization reactions of aromatic aldehydes, resorcinol and malononitrile in the presence of a catalytic amount of Na2CO3 under grinding conditions.